Epione® - Advancing percutaneous tumor ablation with robotic-assisted smart technology
The Epione® robotic-assisted platform is an all-in-one solution integrating all the steps of a percutaneous ablation procedure.
The Epione robotic-assisted percutaneous ablation platform
Epione supports interventional radiologists with percutaneous ablation of abdominal and lung tumors* 1,2.
Compatible with a physician’s preferred ablation technology requiring single or multiple probes (MWA, RFA, cryo, IRE), Epione standardises minimally invasive ablation through image-guided navigation, advanced robotic assistance, and tumor ablation confirmation.
* Epione device is CE marked for abdomen and lung indications, and FDA cleared for abdominal ablation indication.
- Epione® Confirmation Software helps you confirm tumor margin immediately following the procedure
Epione® Planning Software
- Scan and fuse pre-procedure MRI and intra-op CT images for improved tumor visualization
- Epione® Smart Segmentation tool enables quick tumor segmentation
- Epione® Smart Planning module efficiently targets tumors with your preferred technology (MWA, RFA, cryo, IRE) using predefined/preset multi-needle patterns to achieve precise, optimal positioning and coverage
- Epione® Smart Control module allows quick
- Check for correct placement of needles
Epione® Confirmation Software
- Fuse pre- and post-ablation images
- Easily visualize and assess minimal ablative margin to ensure adequate coverage
Patient reference
- The low-profile patient reference allows clear visibility and movement in and out of the CT gantry
- Set reference level to ensure the same level of apnea or jet-ventilation during imaging and probe placement
Watch Epione in action
A streamlined procedural workflow
Epione® gives you an all-in-one solution to Plan, Target, Deliver and Confirm tumor ablation.
Setup
- Flexible wheel-in and wheel-out carts in your CT suites.
- Accommodate your workflow preferences with multiple layout configurations.
Register
- The Patient Reference allows you to register the patient position using the acquired CT scan, enabling needle placement to be performed outside the gantry.
- Set reference level to ensure the same level of apnea or jet-ventilation during imaging and probe placement.
Plan
- Improve tumour visualisation with fused MRI and CT images, and segment tumours in 3D with the Epione® Smart Segmentation tool.
- Epione® Smart Planning module efficiently targets tumours using predefined/preset multi-needle patterns to achieve precise, optimal positioning and coverage.
Target
- Epione® Robotic Arm precisely positions the needle guide at the desired location, angle and depth, and organises the order of multi-needle placements for ease of access.
- Remain in control with manual needle insertion allowing for tactile feedback.
Deliver
- Epione® Smart Control module verifies accuracy of needle placement and allows modification of the treatment plan, if needed.
- Limit radiation exposure to physicians5 with needle placements performed outside the gantry.
Confirm
- Epione® Confirmation Software fuses pre- and post-ablation images to easily visualise and assess minimal ablative margin.
- The ACCLAIM Trial approves of Epione® Confirmation Software for its participating institution sites, requiring them to confirm achieved ablation margins intraprocedurally.
Clinical experiences
The Epione robotic system is being utilized by world-renown hospitals — benefitting over 900 patients globally. Learn more about how Epione can transform your interventional oncology program through first-hand clinician experiences and clinical evidence.
Epione user testimonials
The technical difficulty involved in placing the needle (or needles) is reduced, and I can focus on patient safety and the oncological efficacy of tumour destruction.
The needles are placed exactly where we predicted they would be. With the human hand, the needles are approximately where we predicted
With Epione, you just have to identify the volume of the tumor, click on the center of it, and pick the number of needles that you’re going to use. It gives you a trajectory for all needles that you’re going to place. Everything is done with one click, so it saves a significant amount of time.
Meet Epione
The Epione robotic system regularly travels to interventional oncology conferences in the U.S. and Europe. Find out where Epione is going next — and let’s meet up!
Epione, a fast-evolving robotic platform
These updates include approvals for new indications, hardware & software updates, expansion of ablation needle compatibility, new accessories, made possible by partnering with top international interventional oncologists, interventional radiologists and surgeons.
Moreover, Quantum Surgical works very closely with its Scientific Advisory Board. Made of highly skilled experts, they provide their insights and advice to accelerate the the Epione robot adoption, as well as to guide the company’s choices and development options in alignment with emerging clinical challenges on a global scale.
Prof. Steven D. Colquhoun (USA)
Prof. Thierry de Baere (FR)
Prof. Laurent Milot (FR)
Dr. Govindarajan Narayanan (USA)
Prof. Luigi Solbiati (IT)
Dr. Sean Tutton (USA)
Epione® standardizes ablation procedures with an integrated and streamlined workflow. It integrates all the steps of a percutaneous ablation in 4 simple steps: plan, target, deliver and confirm.
Epione® is an all-in-one solution designed to:
• Plan and confirm needle placement with 3D ablation zone overlays Improve needle placement accuracy and account for real-time patient respiration movement
• Target challenging tumors with precise multi-needle placements and oblique trajectories
• Shorten needle insertion time while utilizing preferred ablation device (MW/RF/CRYO/IRE)
• Limit radiation exposure with needle placements performed outside the gantry
• Confirm adequate tumor margin coverage immediately following the procedure
Epione is commercially available in Europe and in the USA.Epione device is CE marked for abdomen (including liver, kidney, pancreas) and lung indications, and FDA cleared for abdominal ablation indication 1,2.
Please visit our Testimonials page for more info.
Although some robotic systems are available on the market, the vast majority of percutaneous ablation procedures are still carried out conventionally today, meaning they are done manually. The conventional workflow includes manual placement of ablation probes based on pre-procedural imaging and incremental CT scans during the procedure to ensure accuracy.
Epione robotic platform allows physicians to overcome limitations from conventional image-guided percutaneous ablation workflow:
• Planning is done in-procedure (instead of pre-procedure), with real-time 3D and 2D visualization
• Probe accurate placement achieved in minutes, within one apnea thanks to robotic precision
• Workflow efficiency & streamlining thanks to Epione’s open architecture allowing to work with any CT scanner and ablation modality
• Radiation exposure may be reduced with reduced overall number of scans
• Learning curve set in weeks to months.
There are several ways to see the Epione robot in action:
• Attend one of the industry tradeshows such as SIR and CIRSE. Our team and expert spokespersons can show you how Epione works. Find out where we will be next !
• Contact us to request a demo
2. TÜV Rheinland (August 31, 2021). MDR Ann. IX, Chapt I Certificate (Certificate No. HZ 1551912-1). Quantum Surgical SAS. [https://www.certipedia.com/certificates/HZ+1551912-1].
3. Najafi G, Kreiser K, Abdelaziz MEMK, Hamady MS. Current State of Robotics in Interventional Radiology. Cardiovasc Intervent Radiol. 2023;46(5):549-561. doi:10.1007/s00270-023-03421-1.
4. Charalampopoulos G, Bale R, Filippiadis D, Odisio BC, Wood B, Solbiati L. Navigation and Robotics in Interventional Oncology: Current Status and Future Roadmap. Diagnostics (Basel). 2023;14(1):98. Published 2023 Dec 31. doi:10.3390/diagnostics14010098.
5. Bodard S, Guinebert S, Dimopoulos PM, Tacher V, Cornelis FH. Contribution and advances of robotics in percutaneous oncological interventional radiology. Bull Cancer. 2024. doi:10.1016/j. bulcan.2024.06.004.
6. Moschovas MC, Bravi CA, Dell’Oglio P, et al. Current practice and unmet training needs in robotic-assisted radical prostatectomy: investigation from the Junior ERUS/YAU working group. World J Urol. 2024;42(1):59. Published 2024 Jan 27. doi:10.1007/s00345-023-04713-4.
7. Ayabe RI, Azimuddin A, Tran Cao HS. Robot-assisted liver resection: the real benefit so far. Langenbecks Arch Surg. 2022;407(5):1779-1787. doi:10.1007/s00423-022-02523-7.
8. Vernuccio F, Messina C, Merz V, Cannella R, Midiri M. Resectable and Borderline Resectable Pancreatic Ductal Adenocarcinoma: Role of the Radiologist and Oncologist in the Era of Precision Medicine. Diagnostics (Basel). 2021;11(11):2166. Published 2021 Nov 22.
doi:10.3390/diagnostics11112166.
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